Established in 1995, the Aga Khan Higher Secondary School, Karachi (AKHSS) is situated in a 26-acre campus next to the Sultan Muhammad Shah Aga Khan School and the Aga Khan University-Institute for Educational Development. Since its inception, the school has strived to provide quality education to its students.

The foundations of the present education system were laid by Sir Sultan Mohamed Shah Aga Khan III, who established over 200 schools during the 20th century, the first in 1905 in Zanzibar and Gwadar, followed by schools in Dar es Salaam in 1906 and in Mundra, in India, in 1907.

The Aga Khan Higher Secondary School strives to create a harmonious balance between academic demands, sporting and cultural activities and community life. It challenges its pupils to be intellectually inquisitive and socially conscious. The School believes that while what students know is important, the true measure of a student’s education is the ability to analyse what they do not know.

Learning at the School now strengthens the Board of Intermediate Education, Karachi's prescribed curriculum. Education is no longer treated as individual subjects such as Chemistry, Mathematics, Zoology or Economics. Instead, similar subjects are clustered and redefined as a learning area.

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